Palbociclib
Breast cancer
Anticancer Drug (Pyridopyrimidine derivative)
Why Partner with Pinnacle Life Science
Regulatory Compliance
Manufactured under WHO-GMP compliant processes at our US FDA approved facility in Baddi, Himachal Pradesh.
Consistent Quality
Rigorous quality control at every stage ensures reliable purity and potency across every batch produced.
Global Reach
Trusted by pharmaceutical partners and distributors across 90+ countries worldwide.
Mechanism of Action
Palbociclib is a reversible small molecule cyclin-dependent kinase (CDK) inhibitor which is selective for CDK 4 and 6. CDKs have a role in regulating progression through the cell cycle at the G1/S phase by blocking retinoblastoma (Rb) hyperphosphorylation (Finn 2015). Palbociclib reduces proliferation of breast cancer cell lines by preventing progression from the G1 to the S cell cycle phase.
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