Apixaban

Apixaban molecule structure

Anticoagulant Drug (Phenylpiperidines Derivative)

Stroke prevention Deep vein thrombosis Pulmonary embolism

Mechanism of Action

Inhibits platelet activation and fibrin clot formation via direct, selective and reversible inhibition of free and clot-bound factor Xa (FXa). FXa, as part of the prothrombinase complex consisting also of factor Va, calcium ions, and phospholipid, catalyzes the conversion of prothrombin to thrombin.

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