Enzalutamide

Enzalutamide molecule structures

Anticancer Drug (Phenylimidazolidine Derivative)

Prostate cancer

Mechanism of Action

Enzalutamide is a pure androgen receptor signaling inhibitor; unlike other antiandrogen therapies, it has no known agonistic properties. It inhibits androgen receptor nuclear translocation, DNA binding, and coactivator mobilization, leading to cellular apoptosis and decreased prostate tumor volume.

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